Yoshiyuki Asai / 浅井 義之

Group Leader, Staff Scientist
Integrated Open Systems Unit,
Okinawa Institute of Science and Technology Graduate University (OIST)
沖縄科学技術大学院大学
統合オープンシステムユニット
グループリーダー、スタッフサイエンティスト
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Research Interest

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Development of technologies to support multi-scale dynamical system modeling of physiological systems and simulations

 Software that we've been developing
  ・PhysioDesigner.org
  ・Physiome.jp
    - PH Database
    - PhysioVisualizer
    - PH Plotter
    - etc
  ・Flint K3

 Tutorials of PhysioDesigner
  ・YouTube channel of PhysioDesigner
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Theoretical study of dynamics of physiological functions, of neurons, neural networks, pancreas, kidney, heart and so on.

Project description

We have been developing an open platform called “insilico platform”, and now we are developing PhysioDesigner as a successor of the insilico platform. On the platform, physiological functions are considered as an aggregate of “modules”. Based on this modularity, physiological functions are structuralized and modeled. The model is described in insilicoML, an XML based language, which we defined to well describe the modular and hierarchical structure of the models. Using our platform users can integrate not only mathematical expressions but also experimentally obtained timeseries data and morphological data.

Neuroscience is one of scientific areas in which mathematical models have been playing active roles successfully through past decades. Now by combining computational and theoretical neuroscience, systems biology and neurophysiology, a new approach so called neurophysiome is arising. Neuropysiome is one of the targeting area of PhysioDesigner among others.

I am also interested in modeling of Pancreas, Kidney and Heart. Applications of models and simulations to clinical sites are one of important objective of my research.



Okinawa Institute of Science and Technology, Integrated Open Systems Unit, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa, 904-0495, Japan